Dog genetics to understand human diseases


Dogs are more than man’s best friend; they help us understanding better the genetic origin of diseases such as cancer, epilepsy, cardiovascular troubles or diabetes. Living in the same environment, humans and dogs suffer from the same diseases, but dogs’ diseases are genetically a lot simpler.

Since January 2008 twenty veterinary schools from 12 European countries work together to collect DNA samples from purebred dogs; healthy or affected by similar diseases as human. We are currently collecting samples and will greatly appreciate your help (link)

How do we proceed?

The genome of affected dogs is compared to the genome of healthy dogs of the same breed to identify defects implied in the mechanisms of that disease. This project first aims at reducing the high level of inherited canine disease.

Furthermore the identification of genes implied in disease development will allow to understand the mechanisms and pathways of the pathology. Human medicine will ultimately benefit from these results.

Lupa project

The LUPA project was named after the female wolf that fed the twin founders of Rome to reflect the benefits human will obtain from dog genetics. It is a Collaborative Research Project funded by the European Commission under the 7th Research Framework Programme. This website represents the views of the Authors, not of the European Commission.

The Commission is not liable for any use that may be made of the information.


Contact email : info@eurolupa.org